Repeated dose treatment of Tinospora cordifolia polysaccharide rich extract activates splenic antigen presenting cells with no associated organ toxicity

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Glycosyl composition of polysaccharide from Tinospora cordifolia.

Polysaccharide from Tinospora cordifolia was isolated, purified, hydrolysed, trimethylsilylated and then subjected to GC-MC studies. The polysaccharide composition was estimated as follows: glucose 98.0%, arabinose 0.5%, rhamnose 0.2%, xylose 0.8%, mannose 0.2% and galactose 0.3%.

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Glycosyl composition of a polysaccharide from Tinospora cordifolia (Willd.) Miers

Hook. f. & Thoms. (Menispermaceae), which is a succulent climbing shrub distributed throughout most of India, has been reported (1). Polysaccharides are often subjected to different chemical modifications in order to gain information on their sequences and possible configurations. Methylation analysis has proven to be valuable in following the outcome of such modifications. The present work inv...

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Radioprotective potential of an herbal extract of Tinospora cordifolia.

A preparation of Tinospora cordifolia (RTc) administered i.p. (200 mg/kg b.w.) to strain "A" male mice 1 h before whole body gamma-irradiation was evaluated for its radioprotective efficacy in terms of whole body survival, spleen colony forming units (CFU), hematological parameters, cell cycle progression, and micronuclei induction. Preirradiation treatment with RTc rendered 76.3% survival (30 ...

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Effect of aqueous extract of Tinospora cordifolia on

18 BACKGROUND: The current practice of ingesting phytochemicals to support the immune 19 system or to fight infections is based on centuries-old tradition. Macrophages are involved at all 20 stages of the immune response. The present study focuses on immunostimulant properties of 21 Tinospora cordifolia in circulating macrophages of CCl4 (0.5 ml/kg body weight) intoxicated 22 male albino mice. ...

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ژورنال

عنوان ژورنال: Phytomedicine Plus

سال: 2021

ISSN: 2667-0313

DOI: 10.1016/j.phyplu.2021.100065